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Post‐transcriptional regulation of PIAS3 expression by miR‐18a in malignant mesothelioma

Protein inhibitor of activated STAT3 (PIAS3) is an endogenous suppressor of signal transducer and activator of transcription 3 (STAT3) signaling. By directly interacting with phosphorylated STAT3, PIAS3 can block the downstream transcriptional activity of STAT3, which is hyper‐activated in various c...

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Bibliografske podrobnosti
izdano v:Mol Oncol
Main Authors: He, Tian, McColl, Karen, Sakre, Nneha, Chen, Yanwen, Wildey, Gary, Dowlati, Afshin
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275277/
https://ncbi.nlm.nih.gov/pubmed/30259640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12386
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