Quantifying Beta‐Galactosylceramide Kinetics in Cerebrospinal Fluid of Healthy Subjects Using Deuterium Labeling

Therapeutics promoting myelin synthesis may enhance recovery in demyelinating diseases, such as multiple sclerosis. However, no suitable method exists to quantify myelination. The turnover of galactosylceramide (myelin component) is indicative of myelination in mice, but its turnover has not been de...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Kanhai, KMS, Goulooze, SC, Stevens, J, Hay, JL, Dent, G, Verma, A, Hankemeier, T, de Boer, T, Meijering, H, Chavez, JC, Cohen, AF, Groeneveld, GJ
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351000/
https://ncbi.nlm.nih.gov/pubmed/27743499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12424
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