Quantifying Beta‐Galactosylceramide Kinetics in Cerebrospinal Fluid of Healthy Subjects Using Deuterium Labeling

Therapeutics promoting myelin synthesis may enhance recovery in demyelinating diseases, such as multiple sclerosis. However, no suitable method exists to quantify myelination. The turnover of galactosylceramide (myelin component) is indicative of myelination in mice, but its turnover has not been de...

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Dades bibliogràfiques
Publicat a:Clin Transl Sci
Autors principals: Kanhai, KMS, Goulooze, SC, Stevens, J, Hay, JL, Dent, G, Verma, A, Hankemeier, T, de Boer, T, Meijering, H, Chavez, JC, Cohen, AF, Groeneveld, GJ
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351000/
https://ncbi.nlm.nih.gov/pubmed/27743499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12424
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