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The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B
Butyrate response factor (BRF1) belongs to the Tis11 family of CCCH zinc-finger proteins, which bind to mRNAs containing an AU-rich element (ARE) in their 3′ untranslated region and promote their deadenylation and rapid degradation. Independent signal transduction pathways have been reported to stab...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535089/ https://ncbi.nlm.nih.gov/pubmed/15538381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600477 |
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