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The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B

Butyrate response factor (BRF1) belongs to the Tis11 family of CCCH zinc-finger proteins, which bind to mRNAs containing an AU-rich element (ARE) in their 3′ untranslated region and promote their deadenylation and rapid degradation. Independent signal transduction pathways have been reported to stab...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Schmidlin, Martin, Lu, Min, Leuenberger, Sabrina A, Stoecklin, Georg, Mallaun, Michel, Gross, Brigitte, Gherzi, Roberto, Hess, Daniel, Hemmings, Brian A, Moroni, Christoph
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC535089/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15538381/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600477
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