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FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK
Forkhead transcription factors of the FOXO class are negatively regulated by PKB/c-Akt in response to insulin/IGF signalling, and are involved in regulating cell cycle progression and cell death. Here we show that, in contrast to insulin signalling, low levels of oxidative stress generated by treatm...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2004
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535088/ https://ncbi.nlm.nih.gov/pubmed/15538382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600476 |
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