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Regulation of the Forkhead Transcription Factor AFX by Ral-Dependent Phosphorylation of Threonines 447 and 451

AFX is a Forkhead transcription factor that induces a G(1) cell cycle arrest via upregulation of the cell cycle inhibitor p27(Kip1). Previously we have shown that protein kinase B (PKB) phosphorylates AFX causing inhibition of AFX by nuclear exclusion. In addition, Ras, through the activation of the...

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Detalhes bibliográficos
Main Authors: De Ruiter, Nancy D., Burgering, Boudewijn M. T., Bos, Johannes L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99987/
https://ncbi.nlm.nih.gov/pubmed/11689711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.23.8225-8235.2001
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