Regulation of the Forkhead Transcription Factor AFX by Ral-Dependent Phosphorylation of Threonines 447 and 451

AFX is a Forkhead transcription factor that induces a G(1) cell cycle arrest via upregulation of the cell cycle inhibitor p27(Kip1). Previously we have shown that protein kinase B (PKB) phosphorylates AFX causing inhibition of AFX by nuclear exclusion. In addition, Ras, through the activation of the...

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Pubblicato in:	Mol Cell Biol
Autori principali:	De Ruiter, Nancy D., Burgering, Boudewijn M. T., Bos, Johannes L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2001
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99987/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689711/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.23.8225-8235.2001
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