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Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme

Polyamines are essential organic cations with multiple cellular functions. Their synthesis is controlled by a feedback regulation whose main target is ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis. In mammals, ODC has been shown to be inhibited and targeted for ub...

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Detalhes bibliográficos
Main Authors: Palanimurugan, R, Scheel, Hartmut, Hofmann, Kay, Jürgen Dohmen, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535087/
https://ncbi.nlm.nih.gov/pubmed/15538383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600473
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