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Interaction of polyamines and mTOR signaling in the synthesis of antizyme (AZ)

Tissue polyamine levels are largely determined by the activity of ornithine decarboxylase (ODC, EC 4.1.17), which catalyzes the conversion of ornithine to the diamine putrescine. The activity of the enzyme is primarily regulated by a negative feedback mechanism involving ODC antizyme (AZ). Our previ...

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Pubblicato in:Cell Signal
Autori principali: Ray, Ramesh M., Bavaria, Mitul, Johnson, Leonard R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502979/
https://ncbi.nlm.nih.gov/pubmed/26093026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.06.002
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