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Ligand-dependent switching of ubiquitin–proteasome pathways for estrogen receptor
Recent evidence indicates that the transactivation of estrogen receptor α (ERα) requires estrogen-dependent receptor ubiquitination and degradation. Here we show that estrogen-unbound (unliganded) ERα is also ubiquitinated and degraded through a ubiquitin–proteasome pathway. To investigate this ubiq...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535086/ https://ncbi.nlm.nih.gov/pubmed/15538384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600472 |
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