Ligand-dependent switching of ubiquitin–proteasome pathways for estrogen receptor

Recent evidence indicates that the transactivation of estrogen receptor α (ERα) requires estrogen-dependent receptor ubiquitination and degradation. Here we show that estrogen-unbound (unliganded) ERα is also ubiquitinated and degraded through a ubiquitin–proteasome pathway. To investigate this ubiq...

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Autori principali: Tateishi, Yukiyo, Kawabe, Yoh-ichi, Chiba, Tomoki, Murata, Shigeo, Ichikawa, Ken, Murayama, Akiko, Tanaka, Keiji, Baba, Tadashi, Kato, Shigeaki, Yanagisawa, Junn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC535086/
https://ncbi.nlm.nih.gov/pubmed/15538384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600472
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