Turning Off Estrogen Receptor β-Mediated Transcription Requires Estrogen-Dependent Receptor Proteolysis

Recent studies have shed light on the ligand-dependent transactivation mechanisms of nuclear receptors (NRs). When the ligand dose is reduced, the transcriptional activity of NRs should be downregulated. Here we show that a ubiquitin-proteasome pathway plays a key role in turning off transcription m...

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Detalhes bibliográficos
Main Authors: Tateishi, Yukiyo, Sonoo, Raku, Sekiya, Yu-ichi, Sunahara, Nanae, Kawano, Miwako, Wayama, Mitsutoshi, Hirota, Ryuichi, Kawabe, Yoh-ichi, Murayama, Akiko, Kato, Shigeaki, Kimura, Keiji, Yanagisawa, Junn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636734/
https://ncbi.nlm.nih.gov/pubmed/16940184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00713-06
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