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Estrogen Inhibits Transforming Growth Factor β Signaling by Promoting Smad2/3 Degradation
Estrogen is a growth factor that stimulates cell proliferation. The effects of estrogen are mediated through the estrogen receptors, ERα and ERβ, which function as ligand-induced transcription factors and belong to the nuclear receptor superfamily. On the other hand, TGF-β acts as a cell growth inhi...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863224/ https://ncbi.nlm.nih.gov/pubmed/20207742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093039 |
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