The E3 Ubiquitin Ligase Activity of Trip12 Is Essential for Mouse Embryogenesis

Protein ubiquitination is a post-translational protein modification that regulates many biological conditions [1], [2], [3], [4]. Trip12 is a HECT-type E3 ubiquitin ligase that ubiquitinates ARF and APP-BP1 [5], [6]. However, the significance of Trip12 in vivo is largely unknown. Here we show that t...

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Main Authors: Kajiro, Masashi, Tsuchiya, Mai, Kawabe, Yoh-ichi, Furumai, Ryohei, Iwasaki, Naoya, Hayashi, Yuki, Katano, Miyuki, Nakajima, Yuka, Goto, Natsuka, Watanabe, Tatsuya, Murayama, Akiko, Oishi, Hisashi, Ema, Masatsugu, Takahashi, Satoru, Kishimoto, Hiroyuki, Yanagisawa, Junn
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196520/
https://ncbi.nlm.nih.gov/pubmed/22028794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025871
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