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The E3 Ubiquitin Ligase Activity of Trip12 Is Essential for Mouse Embryogenesis
Protein ubiquitination is a post-translational protein modification that regulates many biological conditions [1], [2], [3], [4]. Trip12 is a HECT-type E3 ubiquitin ligase that ubiquitinates ARF and APP-BP1 [5], [6]. However, the significance of Trip12 in vivo is largely unknown. Here we show that t...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196520/ https://ncbi.nlm.nih.gov/pubmed/22028794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025871 |
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