2-(4-Hydroxy-3-methoxyphenyl)-benzothiazole suppresses tumor progression and metastatic potential of breast cancer cells by inducing ubiquitin ligase CHIP

Breast cancer is the most common malignancy among women and has poor survival and high recurrence rates for aggressive metastatic disease. Notably, triple-negative breast cancer (TNBC) is a highly aggressive cancer and there is no preferred agent for TNBC therapy. In this study, we show that a novel...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hiyoshi, Hiromi, Goto, Natsuka, Tsuchiya, Mai, Iida, Keisuke, Nakajima, Yuka, Hirata, Naoya, Kanda, Yasunari, Nagasawa, Kazuo, Yanagisawa, Junn
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235287/
https://ncbi.nlm.nih.gov/pubmed/25403352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07095
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