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Increased Phosphorylation‐Dependent Nuclear Export of Class II Histone Deacetylases in Failing Human Heart

In the failing human heart (FHH) the induction of a fetal contractile protein gene program is directly and selectively associated with the dilated cardiomyopathy (DCM) phenotype and involves multiple signaling pathways. In response to cardiac stress signals, class II HDACs are subject to phosphoryla...

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Publicat a:Clin Transl Sci
Autors principals: Calalb, Mihail B., McKinsey, Timothy A., Newkirk, Scott, Huynh, Khai, Sucharov, Carmen C., Bristow, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350751/
https://ncbi.nlm.nih.gov/pubmed/20443916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2009.00141.x
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