Increased Phosphorylation‐Dependent Nuclear Export of Class II Histone Deacetylases in Failing Human Heart

In the failing human heart (FHH) the induction of a fetal contractile protein gene program is directly and selectively associated with the dilated cardiomyopathy (DCM) phenotype and involves multiple signaling pathways. In response to cardiac stress signals, class II HDACs are subject to phosphoryla...

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Veröffentlicht in:Clin Transl Sci
Hauptverfasser: Calalb, Mihail B., McKinsey, Timothy A., Newkirk, Scott, Huynh, Khai, Sucharov, Carmen C., Bristow, Michael R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Inc 2009
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350751/
https://ncbi.nlm.nih.gov/pubmed/20443916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2009.00141.x
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