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Increased Phosphorylation‐Dependent Nuclear Export of Class II Histone Deacetylases in Failing Human Heart

In the failing human heart (FHH) the induction of a fetal contractile protein gene program is directly and selectively associated with the dilated cardiomyopathy (DCM) phenotype and involves multiple signaling pathways. In response to cardiac stress signals, class II HDACs are subject to phosphoryla...

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Détails bibliographiques
Publié dans:Clin Transl Sci
Auteurs principaux: Calalb, Mihail B., McKinsey, Timothy A., Newkirk, Scott, Huynh, Khai, Sucharov, Carmen C., Bristow, Michael R.
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Inc 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350751/
https://ncbi.nlm.nih.gov/pubmed/20443916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2009.00141.x
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