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Super-enhancer-mediated RNA processing revealed by integrative microRNA network analysis

Super-enhancers are an emerging sub-class of regulatory regions controlling cell identity and disease genes. However, their biological function and impact on miRNA networks are unclear. Here we report that super-enhancers drive the biogenesis of master miRNAs crucial for cell identity by enhancing b...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Suzuki, Hiroshi I., Young, Richard A, Sharp, Phillip A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350633/
https://ncbi.nlm.nih.gov/pubmed/28283057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.02.015
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