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Super-enhancer-mediated RNA processing revealed by integrative microRNA network analysis
Super-enhancers are an emerging sub-class of regulatory regions controlling cell identity and disease genes. However, their biological function and impact on miRNA networks are unclear. Here we report that super-enhancers drive the biogenesis of master miRNAs crucial for cell identity by enhancing b...
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| Publicado no: | Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5350633/ https://ncbi.nlm.nih.gov/pubmed/28283057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.02.015 |
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