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MicroRNA sponges: Progress and possibilities

The microRNA (miRNA) “sponge” method was introduced three years ago as a means to create continuous miRNA loss of function in cell lines and transgenic organisms. Sponge RNAs contain complementary binding sites to a miRNA of interest, and are produced from transgenes within cells. As with most miRNA...

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Bibliographic Details
Main Authors: Ebert, Margaret S., Sharp, Phillip A.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957044/
https://ncbi.nlm.nih.gov/pubmed/20855538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2414110
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