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MicroRNA sponges: Progress and possibilities

The microRNA (miRNA) “sponge” method was introduced three years ago as a means to create continuous miRNA loss of function in cell lines and transgenic organisms. Sponge RNAs contain complementary binding sites to a miRNA of interest, and are produced from transgenes within cells. As with most miRNA...

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Библиографические подробности
Главные авторы: Ebert, Margaret S., Sharp, Phillip A.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957044/
https://ncbi.nlm.nih.gov/pubmed/20855538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2414110
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