Protein synthesis inhibition and GADD34 control IFN‐β heterogeneous expression in response to dsRNA

In innate immune responses, induction of type‐I interferons (IFNs) prevents virus spreading while viral replication is delayed by protein synthesis inhibition. We asked how cells perform these apparently contradictory activities. Using single fibroblast monitoring by flow cytometry and mathematical...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Dalet, Alexandre, Argüello, Rafael J, Combes, Alexis, Spinelli, Lionel, Jaeger, Sebastien, Fallet, Mathieu, Vu Manh, Thien‐Phong, Mendes, Andreia, Perego, Jessica, Reverendo, Marisa, Camosseto, Voahirana, Dalod, Marc, Weil, Tobias, Santos, Manuel A, Gatti, Evelina, Pierre, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350567/
https://ncbi.nlm.nih.gov/pubmed/28100675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695000
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