Protein synthesis inhibition and GADD34 control IFN‐β heterogeneous expression in response to dsRNA

In innate immune responses, induction of type‐I interferons (IFNs) prevents virus spreading while viral replication is delayed by protein synthesis inhibition. We asked how cells perform these apparently contradictory activities. Using single fibroblast monitoring by flow cytometry and mathematical...

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Publicado en:EMBO J
Autores principales: Dalet, Alexandre, Argüello, Rafael J, Combes, Alexis, Spinelli, Lionel, Jaeger, Sebastien, Fallet, Mathieu, Vu Manh, Thien‐Phong, Mendes, Andreia, Perego, Jessica, Reverendo, Marisa, Camosseto, Voahirana, Dalod, Marc, Weil, Tobias, Santos, Manuel A, Gatti, Evelina, Pierre, Philippe
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350567/
https://ncbi.nlm.nih.gov/pubmed/28100675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695000
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