A Drosophila model of Fragile X syndrome exhibits defects in phagocytosis by innate immune cells

Fragile X syndrome, the most common known monogenic cause of autism, results from the loss of FMR1, a conserved, ubiquitously expressed RNA-binding protein. Recent evidence suggests that Fragile X syndrome and other types of autism are associated with immune system defects. We found that Drosophila...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: O’Connor, Reed M., Stone, Elizabeth F., Wayne, Charlotte R., Marcinkevicius, Emily V., Ulgherait, Matt, Delventhal, Rebecca, Pantalia, Meghan M., Hill, Vanessa M., Zhou, Clarice G., McAllister, Sophie, Chen, Anna, Ziegenfuss, Jennifer S., Grueber, Wesley B., Canman, Julie C., Shirasu-Hiza, Mimi M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350515/
https://ncbi.nlm.nih.gov/pubmed/28223318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607093
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