Forkhead Protein FoxO1 Acts as a Repressor to Inhibit Cell Differentiation in Human Fetal Pancreatic Progenitor Cells

Our colleagues have reported previously that human pancreatic progenitor cells can readily differentiate into insulin-containing cells. Particularly, transplantation of these cell clusters upon in vitro induction for 3-4 w partially restores hyperglycemia in diabetic nude mice. In this study, we use...

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Veröffentlicht in:J Diabetes Res
Hauptverfasser: Jiang, Zongzhe, Tian, Jingjing, Zhang, Wenjian, Yan, Hao, Liu, Liping, Huang, Zhenhe, Lou, Jinning, Ma, Xiaosong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350409/
https://ncbi.nlm.nih.gov/pubmed/28349071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6726901
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