Cell Cycle Inhibition by FoxO Forkhead Transcription Factors Involves Downregulation of Cyclin D

The FoxO forkhead transcription factors FoxO4 (AFX), FoxO3a (FKHR.L1), and FoxO1a (FKHR) represent important physiological targets of phosphatidylinositol-3 kinase (PI3K)/protein kinase B (PKB) signaling. Overexpression or conditional activation of FoxO factors is able to antagonize many responses t...

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Detalhes bibliográficos
Main Authors: Schmidt, Marc, de Mattos, Sylvia Fernandez, van der Horst, Armando, Klompmaker, Rob, Kops, Geert J. P. L, Lam, Eric W.-F., Burgering, Boudewijn M. T., Medema, René H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134724/
https://ncbi.nlm.nih.gov/pubmed/12391153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.22.7842-7852.2002
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