Inhibition of Nuclear Import by Protein Kinase B (Akt) Regulates the Subcellular Distribution and Activity of the Forkhead Transcription Factor AFX

AFX belongs to a subfamily of Forkhead transcription factors that are phosphorylated by protein kinase B (PKB), also known as Akt. Phosphorylation inhibits the transcriptional activity of AFX and changes the steady-state localization of the protein from the nucleus to the cytoplasm. Our goal was thr...

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Bibliografiset tiedot
Päätekijät: Brownawell, Amy M., Kops, Geert J. P. L., Macara, Ian G., Burgering, Boudewijn M. T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2001
Aiheet:
Nucleocytoplasmic Communication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC100275/
https://ncbi.nlm.nih.gov/pubmed/11313479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.10.3534-3546.2001
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