Inhibition of Nuclear Import by Protein Kinase B (Akt) Regulates the Subcellular Distribution and Activity of the Forkhead Transcription Factor AFX

AFX belongs to a subfamily of Forkhead transcription factors that are phosphorylated by protein kinase B (PKB), also known as Akt. Phosphorylation inhibits the transcriptional activity of AFX and changes the steady-state localization of the protein from the nucleus to the cytoplasm. Our goal was thr...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Brownawell, Amy M., Kops, Geert J. P. L., Macara, Ian G., Burgering, Boudewijn M. T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Nucleocytoplasmic Communication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11313479/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.10.3534-3546.2001
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