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Reduced responses to glutamate receptor agonists follow loss of astrocytes and astroglial glutamate markers in the nucleus tractus solitarii

Saporin (SAP) or SAP conjugates injected into the nucleus tractus solitarii (NTS) of rats kill astrocytes. When injected in its unconjugated form, SAP produces no demonstrable loss of or damage to local neurons. However bilateral injections of SAP significantly attenuate responses to activation of b...

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Detalles Bibliográficos
Publicado en:Physiol Rep
Main Authors: Talman, William T., Dragon, Deidre Nitschke, Lin, Li‐Hsien
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350171/
https://ncbi.nlm.nih.gov/pubmed/28270593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13158
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