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Targeting Neurons of Rat Nucleus Tractus Solitarii with the Gene Transfer Vector Adeno-Associated Virus Type 2 to Up-Regulate Neuronal Nitric Oxide Synthase

Adeno-associated virus (AAV) has distinct advantages over other viral vectors in delivering genes of interest to the brain. AAV mainly transfects neurons, produces no toxicity or inflammatory responses, and yields long-term transgene expression. In this study, we first tested the hypothesis that AAV...

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Hlavní autoři: Lin, Li-Hsien, Dragon, Deidre Nitschke, Jin, Jingwen, Talman, William T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146586/
https://ncbi.nlm.nih.gov/pubmed/21431420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-011-9674-5
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