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Targeting Neurons of Rat Nucleus Tractus Solitarii with the Gene Transfer Vector Adeno-Associated Virus Type 2 to Up-Regulate Neuronal Nitric Oxide Synthase

Adeno-associated virus (AAV) has distinct advantages over other viral vectors in delivering genes of interest to the brain. AAV mainly transfects neurons, produces no toxicity or inflammatory responses, and yields long-term transgene expression. In this study, we first tested the hypothesis that AAV...

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書誌詳細
主要な著者: Lin, Li-Hsien, Dragon, Deidre Nitschke, Jin, Jingwen, Talman, William T.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146586/
https://ncbi.nlm.nih.gov/pubmed/21431420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-011-9674-5
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