Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons

Alterations in NGF/TrkA signaling have been suggested to underlie the selective degeneration of the cholinergic basal forebrain neurons occurring in vivo in AD (Counts and Mufson, 2005; Mufson et al., 2008; Niewiadomska et al., 2011) and significant reduction of cognitive decline along with an impro...

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Publicat a:Front Cell Neurosci
Autors principals: Latina, Valentina, Caioli, Silvia, Zona, Cristina, Ciotti, Maria T., Amadoro, Giuseppina, Calissano, Pietro
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350152/
https://ncbi.nlm.nih.gov/pubmed/28360840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00068
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