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Histones facilitate α-synuclein aggregation during neuronal apoptosis

Ample in vitro and in vivo experimental evidence supports the hypothesis that intercellular transmission of α-synuclein (αS) is a mechanism underlying the spread of αS pathology in Parkinson's disease and related disorders. What remains unexplained is where and how initial transmissible αS aggr...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol
Main Authors: Jiang, Peizhou, Gan, Ming, Yen, Shu-Hui, McLean, Pamela J., Dickson, Dennis W.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350017/
https://ncbi.nlm.nih.gov/pubmed/28004278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1660-z
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