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Suppression of osteopontin inhibits chemically induced hepatic carcinogenesis by induction of apoptosis in mice

Previous clinical reports have found elevated osteopontin (OPN) levels in tumor tissues to be indicative of greater malignancy in human hepatocellular carcinoma (HCC). However, the role of OPN on carcinogenesis and its underlying mechanism remain unclear. In the present study, we investigated the on...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Su-Hyung, Park, Jun-Won, Woo, Sang-Ho, Go, Du-Min, Kwon, Hyo-Jung, Jang, Ja-June, Kim, Dae-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349983/
https://ncbi.nlm.nih.gov/pubmed/27888617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13529
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