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Suppression of osteopontin inhibits chemically induced hepatic carcinogenesis by induction of apoptosis in mice

Previous clinical reports have found elevated osteopontin (OPN) levels in tumor tissues to be indicative of greater malignancy in human hepatocellular carcinoma (HCC). However, the role of OPN on carcinogenesis and its underlying mechanism remain unclear. In the present study, we investigated the on...

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Pubblicato in:Oncotarget
Autori principali: Lee, Su-Hyung, Park, Jun-Won, Woo, Sang-Ho, Go, Du-Min, Kwon, Hyo-Jung, Jang, Ja-June, Kim, Dae-Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349983/
https://ncbi.nlm.nih.gov/pubmed/27888617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13529
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