Peroxiredoxin 2 is essential for maintaining cancer stem cell-like phenotype through activation of Hedgehog signaling pathway in colon cancer

Cancer stem cells (CSCs) are a key target for reducing tumor growth, metastasis, and recurrence. Redox status is a critical factor in the maintenance of CSCs, and the antioxidant enzyme Peroxiredoxin 2 (Prdx2) plays an important role in the development of colon cancer. Therefore, we investigated the...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Wang, Rong, Wei, Jinlai, Zhang, Shouru, Wu, Xingye, Guo, Jinbao, Liu, Maoxi, Du, Kunli, Xu, Jun, Peng, Linglong, Lv, Zhenbing, You, Wenxian, Xiong, Yongfu, Fu, Zhongxue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349956/
https://ncbi.nlm.nih.gov/pubmed/27894099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13559
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