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Prediction and Validation of Hub Genes Associated with Colorectal Cancer by Integrating PPI Network and Gene Expression Data

Although hundreds of colorectal cancer- (CRC-) related genes have been screened, the significant hub genes still need to be further identified. The aim of this study was to identify the hub genes based on protein-protein interaction network and uncover their clinical value. Firstly, 645 CRC patients...

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Détails bibliographiques
Publié dans:Biomed Res Int
Auteurs principaux: Xiong, Yongfu, You, Wenxian, Wang, Rong, Peng, Linglong, Fu, Zhongxue
Format: Artigo
Langue:Inglês
Publié: Hindawi 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676348/
https://ncbi.nlm.nih.gov/pubmed/29209625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2421459
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