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Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors

Lgr6+ cells have been identified as a novel class of proliferating (Ki67+) stem cells in mouse epidermis. We investigated their response to UV exposure in Lgr6-EGFP-Ires-CreERT2/R26R-LacZ haired and hairless mice and whether they become initiating cells of UV- or chemically induced skin tumors. UV o...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: van de Glind, Gerline C., Rebel, Heggert G., Out-Luiting, Jacoba J., Zoutman, Wim, Tensen, Cornelis P., de Gruijl, Frank R.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349950/
https://ncbi.nlm.nih.gov/pubmed/27880932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13436
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