Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia

The induction of skin cancer involves both mutagenic and proliferative responses of the epidermis to ultraviolet (UV) light. It is believed that tumor initiation requires the mutagenic replication of damaged DNA by translesion synthesis (TLS) pathways. The mechanistic basis for the induction of prol...

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Библиографические подробности
Главные авторы: Tsaalbi-Shtylik, Anastasia, Verspuy, Johan W. A., Jansen, Jacob G., Rebel, Heggert, Carlée, Leone M., van der Valk, Martin A., Jonkers, Jos, de Gruijl, Frank R., de Wind, Niels
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2009
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799833/
https://ncbi.nlm.nih.gov/pubmed/20007784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909507106
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