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Excision of translesion synthesis errors orchestrates responses to helix-distorting DNA lesions

In addition to correcting mispaired nucleotides, DNA mismatch repair (MMR) proteins have been implicated in mutagenic, cell cycle, and apoptotic responses to agents that induce structurally aberrant nucleotide lesions. Here, we investigated the mechanistic basis for these responses by exposing cell...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Tsaalbi-Shtylik, Anastasia, Ferrás, Cristina, Pauw, Bea, Hendriks, Giel, Temviriyanukul, Piya, Carlée, Leone, Calléja, Fabienne, van Hees, Sandrine, Akagi, Jun-Ichi, Iwai, Shigenori, Hanaoka, Fumio, Jansen, Jacob G., de Wind, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395481/
https://ncbi.nlm.nih.gov/pubmed/25869665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408017
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