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Excision of translesion synthesis errors orchestrates responses to helix-distorting DNA lesions

In addition to correcting mispaired nucleotides, DNA mismatch repair (MMR) proteins have been implicated in mutagenic, cell cycle, and apoptotic responses to agents that induce structurally aberrant nucleotide lesions. Here, we investigated the mechanistic basis for these responses by exposing cell...

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Vydáno v:J Cell Biol
Hlavní autoři: Tsaalbi-Shtylik, Anastasia, Ferrás, Cristina, Pauw, Bea, Hendriks, Giel, Temviriyanukul, Piya, Carlée, Leone, Calléja, Fabienne, van Hees, Sandrine, Akagi, Jun-Ichi, Iwai, Shigenori, Hanaoka, Fumio, Jansen, Jacob G., de Wind, Niels
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395481/
https://ncbi.nlm.nih.gov/pubmed/25869665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408017
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