Myb expression is critical for myeloid leukemia development induced by Setbp1 activation

SETBP1 missense mutations have been frequently identified in multiple myeloid neoplasms; however, their oncogenic potential remains unclear. Here we show that expression of Setbp1 mutants carrying two such mutations in mouse bone marrow progenitors efficiently induced development of acute myeloid le...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Nguyen, Nhu, Vishwakarma, Bandana A., Oakley, Kevin, Han, Yufen, Przychodzen, Bartlomiej, Maciejewski, Jaroslaw P., Du, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349915/
https://ncbi.nlm.nih.gov/pubmed/27863435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13383
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi