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Myb expression is critical for myeloid leukemia development induced by Setbp1 activation
SETBP1 missense mutations have been frequently identified in multiple myeloid neoplasms; however, their oncogenic potential remains unclear. Here we show that expression of Setbp1 mutants carrying two such mutations in mouse bone marrow progenitors efficiently induced development of acute myeloid le...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5349915/ https://ncbi.nlm.nih.gov/pubmed/27863435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13383 |
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