Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis

BACKGROUND: Nonseminomatous germ cell tumor of the testis (NSGCT) is largely curable. However, a small group of patients develop refractory disease. We investigated the hypothesis that intratumoral heterogeneity contributes to the emergence of chemoresistance and the development of refractory tumor...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Bilen, Mehmet Asim, Hess, Kenneth R., Campbell, Matthew T., Wang, Jennifer, Broaddus, Russell R., Karam, Jose A., Ward, John F., Wood, Christopher G., Choi, Seungtaek L., Rao, Priya, Zhang, Miao, Naing, Aung, General, Rosale, Cauley, Diana H., Lin, Sue-Hwa, Logothetis, Christopher J., Pisters, Louis L., Tu, Shi-Ming
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349913/
https://ncbi.nlm.nih.gov/pubmed/27861143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13380
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