Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis

BACKGROUND: Nonseminomatous germ cell tumor of the testis (NSGCT) is largely curable. However, a small group of patients develop refractory disease. We investigated the hypothesis that intratumoral heterogeneity contributes to the emergence of chemoresistance and the development of refractory tumor...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Bilen, Mehmet Asim, Hess, Kenneth R., Campbell, Matthew T., Wang, Jennifer, Broaddus, Russell R., Karam, Jose A., Ward, John F., Wood, Christopher G., Choi, Seungtaek L., Rao, Priya, Zhang, Miao, Naing, Aung, General, Rosale, Cauley, Diana H., Lin, Sue-Hwa, Logothetis, Christopher J., Pisters, Louis L., Tu, Shi-Ming
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349913/
https://ncbi.nlm.nih.gov/pubmed/27861143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13380
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