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Intratumoral heterogeneity: Role of differentiation in a potentially lethal phenotype of testicular cancer

BACKGROUND: Intratumoral heterogeneity presents a major obstacle to the widespread implementation of precision medicine. The authors assessed the origin of intratumoral heterogeneity in nonseminomatous germ cell tumor of the testis (NSGCT) and identified distinct tumor subtypes and a potentially let...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Tu, Shi‐Ming, Bilen, Mehmet Asim, Hess, Kenneth R., Broaddus, Russell R., Kopetz, Scott, Wei, Chongjuan, Pagliaro, Lance C., Karam, Jose A., Ward, John F., Wood, Christopher G., Rao, Priya, Tu, Zachary H., General, Rosale, Chen, Adrienne H., Nieto, Yago L., Yeung, Sai‐ching J., Lin, Sue‐Hwa, Logothetis, Christopher J., Pisters, Louis L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071733/
https://ncbi.nlm.nih.gov/pubmed/27018785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29996
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