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Intratumoral heterogeneity: Role of differentiation in a potentially lethal phenotype of testicular cancer

BACKGROUND: Intratumoral heterogeneity presents a major obstacle to the widespread implementation of precision medicine. The authors assessed the origin of intratumoral heterogeneity in nonseminomatous germ cell tumor of the testis (NSGCT) and identified distinct tumor subtypes and a potentially let...

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Podrobná bibliografie
Vydáno v:Cancer
Hlavní autoři: Tu, Shi‐Ming, Bilen, Mehmet Asim, Hess, Kenneth R., Broaddus, Russell R., Kopetz, Scott, Wei, Chongjuan, Pagliaro, Lance C., Karam, Jose A., Ward, John F., Wood, Christopher G., Rao, Priya, Tu, Zachary H., General, Rosale, Chen, Adrienne H., Nieto, Yago L., Yeung, Sai‐ching J., Lin, Sue‐Hwa, Logothetis, Christopher J., Pisters, Louis L.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071733/
https://ncbi.nlm.nih.gov/pubmed/27018785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29996
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