Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis

BACKGROUND: Nonseminomatous germ cell tumor of the testis (NSGCT) is largely curable. However, a small group of patients develop refractory disease. We investigated the hypothesis that intratumoral heterogeneity contributes to the emergence of chemoresistance and the development of refractory tumor...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bilen, Mehmet Asim, Hess, Kenneth R., Campbell, Matthew T., Wang, Jennifer, Broaddus, Russell R., Karam, Jose A., Ward, John F., Wood, Christopher G., Choi, Seungtaek L., Rao, Priya, Zhang, Miao, Naing, Aung, General, Rosale, Cauley, Diana H., Lin, Sue-Hwa, Logothetis, Christopher J., Pisters, Louis L., Tu, Shi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349913/
https://ncbi.nlm.nih.gov/pubmed/27861143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13380
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