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MicroRNA-532 and microRNA-3064 inhibit cell proliferation and invasion by acting as direct regulators of human telomerase reverse transcriptase in ovarian cancer

Human telomerase reverse transcriptase (hTERT) plays a crucial role in ovarian cancer (OC) progression. However, the mechanisms underlying hTERT upregulation in OC, and the specific microRNAs (miRNAs) involved in the regulation of hTERT in OC cells, remains unclear. We performed a bioinformatics sea...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Bai, Lin, Wang, Hui, Wang, Ai-Hua, Zhang, Luo-Ying, Bai, Jie
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349679/
https://ncbi.nlm.nih.gov/pubmed/28291810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173912
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