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Epithelial LTβR signaling controls the population size of the progenitors of medullary thymic epithelial cells in neonatal mice

The establishment of T cell central tolerance critically relies on the development and maintenance of the medullary thymic epithelial cells (mTECs). Disrupted signaling of lymphotoxin beta receptor (LTβR) results in dramatically reduced mTEC population. However, whether LTβR directly or indirectly c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Weiwei, Shi, Yaoyao, Xia, Huan, Chai, Qian, Jin, Caiwei, Ren, Boyang, Zhu, Mingzhao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349570/
https://ncbi.nlm.nih.gov/pubmed/28290551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44481
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