Deciphering the interplay between cysteine synthase and thiol cascade proteins in modulating Amphotericin B resistance and survival of Leishmania donovani under oxidative stress

Leishmania donovani is the causative organism of the neglected human disease known as visceral leishmaniasis which is often fatal, if left untreated. The cysteine biosynthesis pathway of Leishmania may serve as a potential drug target because it is different from human host and regulates downstream...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Singh, Kuljit, Ali, Vahab, Pratap Singh, Krishn, Gupta, Parool, Suman, Shashi S., Ghosh, Ayan K., Bimal, Sanjiva, Pandey, Krishna, Das, Pradeep
Format: Artigo
Language:Inglês
Published: Elsevier 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349463/
https://ncbi.nlm.nih.gov/pubmed/28288415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.03.004
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