Stage-Dependent Expression and Up-Regulation of Trypanothione Synthetase in Amphotericin B Resistant Leishmania donovani

Kinetoplastids differ from other organisms in their ability to conjugate glutathione and spermidine to form trypanothione which is involved in maintaining redox homeostasis and removal of toxic metabolites. It is also involved in drug resistance, antioxidant mechanism, and defense against cellular o...

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Detalhes bibliográficos
Main Authors: Equbal, Asif, Suman, Shashi Shekhar, Anwar, Shadab, Singh, Krishn Pratap, Zaidi, Amir, Sardar, Abul Hasan, Das, Pradeep, Ali, Vahab
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046939/
https://ncbi.nlm.nih.gov/pubmed/24901644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097600
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