Intracellular zinc flux causes reactive oxygen species mediated mitochondrial dysfunction leading to cell death in Leishmania donovani

Leishmaniasis caused by Leishmania parasite is a global threat to public health and one of the most neglected tropical diseases. Therefore, the discovery of novel drug targets and effective drug is a major challenge and an important goal. Leishmania is an obligate intracellular parasite that alterna...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kumari, Anjali, Singh, Krishn Pratap, Mandal, Abhishek, Paswan, Ranjeet Kumar, Sinha, Preeti, Das, Pradeep, Ali, Vahab, Bimal, Sanjiva, Lal, Chandra Shekhar
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460814/
https://ncbi.nlm.nih.gov/pubmed/28586364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178800
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