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The use of small-molecule structures to complement protein–ligand crystal structures in drug discovery

Many ligand-discovery stories tell of the use of structures of protein–ligand complexes, but the contribution of structural chemistry is such a core part of finding and improving ligands that it is often overlooked. More than 800 000 crystal structures are available to the community through the Camb...

詳細記述

保存先:
書誌詳細
出版年:Acta Crystallogr D Struct Biol
主要な著者: Groom, Colin R., Cole, Jason C.
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349436/
https://ncbi.nlm.nih.gov/pubmed/28291759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798317000675
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